"What are stem cells?"
By: Dr. Phil Aaron
We live in a changing world. A world where our health is important to each
of us - important to all of us are the changes, the advances being made in
medical research which will eventually be available to individual patients.
We are able to transplant hearts and reattach severed limbs. This article
will review advances being made in an area of medical research which will
revolutionize our future; and it all starts at the level of the human cell.
Five years ago, Dr. Chris Shields, a Louisville neurosurgeon and chair of
the University of Louisville's Department of Neurosurgery, invited Lance Burton
and his mother, Hilma, my son, Blake and me to Louisville to tour the
University's facilities devoted to neurosurgical research.
Lance's mother, Hilma, and sister, Robyn, had both been operated on
successfully by Dr. Shield's team. Shields wanted to show us how far advanced
neurosurgical research was. He remarked that research such as that going on in
his laboratories and elsewhere across the country was starting to show dramatic
results; that even though spinal cord fusion (putting back together a cord cut
in two) had never yet been accomplished, the time was rapidly approaching when
this would happen.
Then Wham, Bam!!! Eureka! The startling news last month out of the University
of Louisville that their researchers had discovered part of the information
necessary to solve the transplant puzzle: the "lost ark".
The research focused on what we call stem cells.
Stem cells are cells from certain parts of our body which can change their
function-cells which initially work as muscle, brain or spinal cord cells may
eventually be able to change and function as other types of cells. Today when
blood is transfused these regular blood cells eventually die. Stem cells will
not die but would be transfused into a person's body and programmed to function,
perhaps change into another body part. This organ would live for a lifetime.
So, if an individual has a heart attack, in the future stem cells might
replace and repair the dead heart cells making the person's heart healthy again.
One might imagine other diseases which could be cured through stem cell use,
eg. Alzheimer's, Diabetes, Parkinson's, Cancer and many others.
Tonya Ballou has talked with Tim's University of Kentucky Medical Center's
doctors as to whether stem cell research might be a possibility for Tim. The
answer, "Not yet."
Controversies
As we become excited about the great possibilities that Stem Cell research
has, one must note that there is great debate, controversy over such research.
The debate focuses on the location from where the stem cells originate.
Heretofore, the only type of cells which have been able to be programmed to
assume the function of a certain body part, eg. heart/brain have come from human
embryo tissue. Debate has documented on whether embryonic tissue should be used
for such research.
Should embryonic tissue be used?
Bush says no. The late Christopher Reeve (Superman) and Nancy Reagan say
yes.
There are ethical, moral, even biblical debates about using such tissues.
President Bush, eg., has limited the circumstances under which human embryonic
tissue can be used for stem cell research in the United States. Because of this
many researchers have left the U.S. to conduct their research where there are no
such restrictions.
However, the team at the University of Louisville recently found a way to
produce the same results using tissue without an embryological connection.
Non-Embryo Tissue Stem Cell Research=All are happy.
It now appears that one of the greatest challenges of medical research today
- those involving Stem Cells may be pursued within the context of moral, ethical
and Biblical scholarship.